Common Questions About TruAge
TruAge is an at-home sample collection kit.
Upon receiving your sample, our laboratory looks at an epigenetic marker called DNA Methylation, and use the latest research and technology to create an accurate, scientifically verified assessment of your Biological Age.
What is TruDiagnostic?
TruDiagnostic is a state-of-the-art epigenetics laboratory in Lexington, Kentucky. We offer epigenetic analysis for both clinical practitioners, and the public.
We currently focus on the Epigenetic analysis of Aging, and are trusted by a wide network of medical doctors across the world.
Our R&D team's long-term mission is to evolve our testing abilities to one day offer direct diagnosis of diseases, by reading epigenetic markers.
What is TruAge?
TruAge is an easy to use, at-home sample collection kit. It includes all of the tools needed to collect a few drops of blood for the epigenetic analysis. (It's exactly like little fingertip blood draw to test your iron levels at a blood donation center - nothing intravenous)
Once the sample is sent back to our lab for processing and analysis. You can learn more about what happens in our laboratory here. Within 2-3 weeks you'll receive an in-depth report of your Biological Age.
What is Epigenetics?
"Epigenetics refers to heritable changes in gene expression that do not alter the primary DNA sequence."
Epi-Genetics | Above the Genes
In layman's terms - your DNA is basically like a giant recipe book. The genes (sections of the DNA) act as specific steps in the recipes, and control how every part of your body is built, and how it functions.
These genes are on (expressed) or off (not expressed), and can be partially expressed, like a dimmer switch.
Epigenetics is how your environment and lifestyle changes your gene expression. Things like nutrition, smoking, stress, sleep habits - can all change your gene expression.
What is Biological Age?
Biological Age is how rapidly your body is aging. Chronological Age is how many candles are on your birthday cake, or how many years you've been on this earth. While Chronological Age is just a number that shows the passage of time, Biological Age is a reflection of your body's current health.
Most outward signs of aging and age-related diseases are caused by cells losing function, when their genes stop regulating them appropriately. By slowing down your Biological Aging, you're keeping genes activated that tell your your cells to act younger, longer.
Younger cells heal faster, and do their jobs more efficiently, regardless of how many birthday candles you have.
How do we measure Biological Age?
We look at an epigenetic marker called DNA Methylation.
Methylation is when a little molecule attaches to your DNA and changes expression of the gene in that location.
Our lab uses a complex algorithm to sort through around 900,000 Methylation locations on your genome, to figure out how your pattern compares to the average adult your age.
What influences Biological Aging?
Biological Age consists of what you inherited from your parents, what you developed during your childhood, and everyday lifestyle influences like sleep, stress, smoking, nutrition, exercise habits, and much more.
Since over half of your DNA Methylation is changeable, you can significantly change your Biological Age to increase both your lifespan, and your long-term quality of life as it relates to your health.
Is TruAge like a DNA test?
A regular DNA test looks at what genes you have.
TruAge looks at what genes are expressed.
Because TruAge measures epigenetics (changes in gene expression in response to outside influences), it provides more information than your typical mainstream DNA tests.
While a DNA test can say you have genes that could give you a predisposition to develop certain diseases, Epigenetic tests like TruAge can look at how your lifestyle has increased or decreased the influence of that predisposition. Just having the genes isn't enough. Those genes have to be expressed in a particular way to encourage diseases.
Why does TruAge use blood?
Blood is the most scientifically studied, most accurate, and most comprehensive method of testing Epigenetic Aging.
While we know that saliva or urine is easier to collect, those methods don’t have the rigorous scientific research supporting their accuracy, compared to blood.
As a result, we don’t compromise results for easy collection. With our test, we can guarantee accurate and useful results backed by published clinical studies.