Epigenetic age acceleration in older adults with hematologic malignancies.

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April 4, 2023  │ Varun B. Dwaraka, Ryan Smith

Abstract or Summary

Older adults with hematologic malignancy (HM) are a growing demographic with heterogenous health needs. Chronologic age, performance status and comorbidities impact the selection and intensity of treatments but may not accurately predict treatment toxicity or resiliency. Here, we conducted longitudinal measures of clinical frailty and epigenetic age to explore the relationships between physiologic aging and fitness.